Supplement Stack + Tech.

Bryan Johnson's Supplement Stack:

Optimizing Health: Bryan Johnson's Extensive Supplement Regimen

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Silicon Valley entrepreneur Bryan Johnson adheres to a robust daily supplement routine, comprising over 100 pills, categorized into three main groups:

Longevity Supplements, Supplements for Specific Issues, and Offsetting Dietary Insufficiencies.

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Longevity Supplements: Enhancing Lifespan and Healthspan

Bryan Johnson incorporates supplements targeted at potentially increasing lifespan and improving healthspan. An example is Ca-AKG, a compound tested in mice that demonstrated a 5% increase in male mice's lifespan and a 10% increase in female mice. This category reflects Johnson's commitment to exploring compounds with potential longevity benefits.

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Supplements for Specific Issues: Addressing Targeted Concerns

Another facet of Johnson's regimen includes plants, herbs, and compounds designed to address specific health issues. An example is Viviscal, a supplement containing a blend of shark and mollusk powder, marketed to enhance hair thickness. This category highlights Johnson's tailored approach to supplementing based on specific health concerns.

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Offsetting Dietary Insufficiencies: Maintaining Overall Health

Recognizing potential dietary deficits, Johnson includes vitamins, minerals, and other compounds to offset these insufficiencies and uphold overall health. B vitamins and omega-3 fatty acids are cited as examples, deemed crucial for various bodily functions and essential on Johnson's plant-based diet. While not as glamorous, this category emphasizes the foundational role of essential nutrients in maintaining well-being.

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Conclusion: Bryan Johnson's Approach

By categorizing his extensive pill intake into longevity-focused, issue-specific, and dietary offset supplements, Johnson showcases a nuanced strategy to address various facets of well-being. His commitment to exploring compounds with potential longevity benefits, addressing specific health concerns, and ensuring essential nutrient intake reflects a comprehensive and thoughtful approach to personal health and longevity.​

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Longevity Supplements

(Click On Supplement For Details)

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• Calcium Alpha-ketoglutarate (Ca-AKG)

  • Daily Dose: 2 grams

  • Improves frailty index and increased lifespan in mice. Studies showed a 10% increase in female mice and 5% in male mice. Potential mimicking of caloric restriction, leading to a longer and healthier lifespan.

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• Nicotinamide Riboside (NR) and Nicotinamide Mononucleotide (NMN)

  • Daily Dose: 375 mg of NR or 500 mg of NMN (6x per week)

  • Boosts NAD levels to more youthful levels. Studies show effectiveness in increasing NAD levels, with Bryan's personal experience showing a significant reduction in biological age.

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• Taurine

  • Daily Dose: 2 grams

  • Increased lifespan in mice by 10-12%. Taurine plays a role in various physiological processes, including heart, muscle, immune system, and CNS function.

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• Nordihydroguaiaretic Acid (NDGA)

  • Daily Dose: 50 mg

  • Potential autophagy enhancer, showing a 13% increase in median lifespan and 7% longer maximum lifespan in male mice. Caution for potential liver and kidney toxicity.

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• Aspirin

  • Daily Dose: 81 mg (3x per week)

  • Rationale + Source: Potential increase in lifespan, supported by an 8% increase in median survival in male mice. Also used for hypothyroidism and cardiovascular disease risk reduction.

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Supplements for Specific Issues

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• Ashwagandha

  • Daily Dose: 600 mg

  • Reduces anxiety, improves cortisol management, enhances sleep quality, and increases testosterone levels. Adaptogenic herb with a history of use in Ayurvedic medicine.

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Offsetting Dietary Insufficiencies

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• Sulforaphane 

  • Daily Dose: 17.5 mg

  • Contains sulforaphane with various benefits, including chemoprotection.

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• Pea Protein Powder

  • Daily Recommendation Varies​

  • Helps meet protein standards  

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• Cocoa Flavanols

  • Daily Dose: 500 mg

  • Supports heart and brain health.

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• Coenzyme Q10 (CoQ10)

  • Daily Dose: 100 mg

  • Supports mitochondrial and cardiovascular health, also mentioned for oral health.

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• Dehydroepiandrosterone (DHEA)

  • Daily Dose: 25 mg

  • Blood glucose regulation and potential support for testosterone production.

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• N-Acetyl-L-Cysteine (NAC)

  • Daily Dose: 1,800 mg

  • Boosts glutathione, supporting immune health and the body's ability to handle toxins.

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• Hyaluronic Acid

  • Daily Dose: 300 mg

  • For joint health.

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• L-Tyrosine

  • Daily Dose: 500 mg

  • Precursor to dopamine, possibly taken for motivation and reward pathways.

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• Genistein

  • Daily Dose: 125 mg

  • Supports bone health.

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• Viviscal

  • Daily Dose: 1 pill

  • Marketed for hair thickening.

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• Glucosamine Sulfate 2KCL

  • Daily Dose: 1,500 mg

  • Supports cartilage development and repair.

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• Turmeric With Piperine

  • Daily Dose: 1 gram

  • Anti-inflammatory, supports joint and liver health.

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• Garlic

  • Daily Dose: 2.4 g

  • Supports liver enzymes and cholesterol management.

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• Ginger Root

  • Daily Dose: 2.2 g

  • Blood glucose regulation.

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• Melatonin

  • Daily Dose: 300 mcg

  • Potential compensation for age-related decline.

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• Vitamin B Complex

  • Daily Dose: 0.5 pill (2x per week)

  • Essential micronutrients.

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• Vitamin C

  • Daily Dose: 500 mg

  • Essential micronutrient.

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• Vitamin D-3

  • Daily Dose: 2,000 IU

  • Compensates for limited UV exposure.

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• Vitamin E

  • Daily Dose: 67 mg

  • Essential micronutrient, possible reduced stroke risk.

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• EPA & Vit E

  • Daily Dose: EPA 500 mg / vit E 5 mg

  • Improved liver enzymes and arterial health.

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• Iodine as potassium iodide

  • Daily Dose: 125 mcg

  • Supports thyroid function.

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• K2-MK4

  • Daily Dose: 5 mg

  • Supports bone health.

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• Lithium, as lithium orotate

  • Daily Dose: 1 mg

  • Potential mood stabilization.

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• Lycopene

  • Daily Dose: 10 mg

  • Antioxidant properties.

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• Lysine

  • Daily Dose: 1 gram

  • Control of viral outbreaks.

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• Proferrin

  • Daily Dose: 10 mg

  • Ensures sufficient iron intake.

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• Lutein & Zeaxanthin

  • Daily Dose: 20

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See Bryan Johnson's Blueprint for more in depth details.  We suggest consulting with a physician prior to making extreme dietary changes.  It is essential to consider individual responses to these supplements, and consulting with a healthcare professional is advised, especially if you have pre-existing health conditions or are taking other medications

Bryan Johnson's Enabling Technology:

Note, these are not direct endorsements.  This tech has enabled improvements to a wide array of health factors and individuals.   

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Whoop Fitness Tracker - View Here 

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Whoop helps optimize your health, fitness, and life.  Monitor your sleep, strain, recovery, health, and more. 

Through continues monitoring of physiological data, including heart rate, respiratory rate, resting heart rate variability, skin temperature, blood oxygen levels, daily activity and sleep, this device enables an amazing look into the body's function and overall health. 

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Sleep Heating / Cooling pod for any mattress - View Here

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Dynamically heating and cooling your bed enabling your body to remain at optimal temperatures throughout all phases of sleep.  In addition, some pods feature sensors that measure your respiratory rate, sleep stages, sleep time, resting heart rate, heart rate variability, and more

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Quality sleep is a trending priority.  Allowing your body to fully recover and replenish is a non negotiable. 

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Ring Fitness Tracker - View Here

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Designed to provide accurate insights without disrupting your life.  With precise sensors, many of these rings are able to track heart rate, heart rate variability, temperature, activity, and even monitor sleep. 

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It is a lightweight and non-invasive alternative to measuring the health of your body. 

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Air Purifying Device - View Here

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Through circulating purified air throughout your room, you are able to minimize toxic pollutants that continuously fill our lungs.  Creating a stable and healthy environment will boost your overall wellbeing and support general health. 

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Sunlight Simulators - View Here

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Sunlight simulation can be an effective way to set your circadian rhythms without needing to rely on daylight.  Many of these lamps have proven effective to combat tiredness and promote productivity. 

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Establish an environment that will improve your quality of health and life. 

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Vagus Nerve Stimulator - View Here

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The vagus nerve is know to be associated with relaxation.  Stimulating this nerve through massage or electric stimulation has proven to reduce stress and promote relaxation. 
 

Water Flosser - View Here

This technology has enabled Johnson to maintain almost 0 plaque and healthy gums.  Oral care is linked to improvements in cognitive function, healthspan, and overall health. 

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Tear Duct Stimulator - View Here

Johnson uses a tear duct stimulator to combat dry eye.  This has proven to be an effective method and alternative to constant eyedrops.